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What are the environmental factors that can contribute to Alzheimer's and how can treatments be designed to address them?

Project by Polygence alum Megha

What are the environmental factors that can contribute to Alzheimer's and how can treatments be designed to address them?

Project's result

Presented at the Symposium of Rising Scholars 2023, Published in Research Archive of Rising Scholars 2023, Accepted for Publication to Curieux Academic Journal

They started it from zero. Are you ready to level up with us?

Summary

As of 2023, it is estimated that there are 6.7 million people who are 65 or older that have Alzheimer's in America. Alzheimer's is said to be caused by the misfolding of proteins and the accumulation of these non-functional aggregates in the brain. There have been some genes related to Alzheimer's but they don't account for all cases suggesting that environmental factors have a substantial effect on the onset of the disease. Categories of environmental factors that are related to Alzheimer's include education, pre-existing disease, and lifestyle. This review aims to summarize the findings within these three categories. A greater understanding of these factors could allow for better preventative approaches to address the disease as well as treatment.

Katie

Katie

Polygence mentor

PhD Doctor of Philosophy candidate

Subjects

Neuroscience, Biology

Expertise

Neuroscience, neurobiology, neurological disease/disorder

Review of mentor

Katie did a great job teaching me how to organize a review paper and gave me feedback to make my paper the best it could be.

Megha

Megha

Student

Graduation Year

2024

Project review

I received adequate guidance from Katie in learning how to write and format a research review paper.